Part of Harvard Catalyst at Harvard Medical School, Open.Med supports the clinical and translational research community by building innovative tools that connect researchers to the people, information, and resources they need in order to speed the pace of translational research.

The Open.Med Story

We believe that the key elements for success in clinical and translational research already exist at Harvard, including the intellectual force, technologies, and clinical expertise necessary to reduce the burden of human illness. What was missing was a systematic way for investigators from disparate disciplines and institutions to find each other and form teams, share tools and technologies, obtain seed funding to embark upon new areas of investigation, and receive advanced training and education in the principles and practice of clinical and translational science.  Fostering a culture of innovation and collaboration that encourages the translation of ideas into practice is our focus.

Our Timeline

August 2018

eagle-i Featured in FASEB Webinar

FASEB presented a webinar “Shared Resources 101: Finding, Accessing, Securing Support, and More” that featured tools that support shared science using core facilities. eagle-i was one of the tools highlighted.

July 2018

eagle-i Presented at Midwest Big Data Hub/National Data Service Data Science Tools and Methods workshop

Juliane Schneider presented on what eagle-i is, its history, and potential uses in an increasingly open science environment

June 2018

eagle-i publishes Broeckel Lab stem cell lines

The stem cell lines from the NHBLI-funded Broeckel lab are now in eagle-i. The collection consists of 112 lines from a study on left ventricular hypertrophy.

June 2018

Juliane Schneider, team lead, delivers keynote at Data Science Visualization Institute for Librarians at NCSU

Juliane Schneider presented a keynote address about the importance of building expertise, the ways visualization enhances communication, and how learning technical skills can build a common language between librarians and the researchers they support.

March 2018

Juliane Schneider, team lead, Talks FAIR and Researcher Collaboration at Research Data Alliance (RDA) in Berlin

As co-Chair of the Libraries for Research Data interest group, Juliane helped lead a 90 minute discussion on the FAIR data principles, how to collaborate with researchers, and how to support best data practices across disciplines.

January 2018

SMART IRB Online Reliance System Launches

Use the Online Reliance System to determine a reliance arrangement for your study in accordance with the NIH Single IRB Review policy.

December 2017

eagle-i Team Unveils N-Lighten Proof of Concept Discovery Tool

Partnering with The Ohio State University and Oregon Health & Science University, the eagle-i team have used the eagle-i platform combined with a new ontology to create a proof-of-concept discovery tool for educational resources.

May 2017

SMART IRB Online Reliance System in Beta

Request, track, and document reliance arrangements via a nationally connected system for single IRB review.

February 2017

Scheduler Open Source Software Gains Interest

Increased interest in adopting Scheduler open source from institutions such as UCSF, HSPH, University of Colorado, Dartmouth, Stanford.

November 2016

Scheduler Integrates with Epic

Scheduler has successfully integrated with Epic, Partner’s EMPI system for all subject information. Scheduler went live in integration mode at MGH in November 2016 and at BWH in February 2017.

September 2016

SMART IRB Website and Joinder Tool Launch

Single IRB review for multisite studies goes national!

June 2016

Resources available in eagle-i continue to expand

The eagle-i Network now offers over 100,000 resources for the research community! This was accomplished after publishing hundreds of additional cell lines this month.

May 2016

New Functionalities Added to SHRINE

In response to user feedback, query results are available as a graphical display and can be exported as a CSV file.

April 2016

IRBrely prototype 2 completed

We’re building a national IRB reliance network to reduce the administrative burden for multi-site research studies.

March 2016

Harvard Launches ResearchKit App to Support Football Player Health

TeamStudy, an app that is part of the Football Players Health Study at Harvard University, uses ResearchKit to help former NFL players and the public better understand brain function, heart health, pain, and mobility.

March 2016

Scheduler is now Open Source

Visit our open source wiki space for more information on how to download and install the software.

December 2015

Two New SHRINE Networks

The SHRINE open source software is used in two new national networks. These are the biggest networks to date, and prove SHRINE’s ability to scale to ever-larger implementations.

October 2015

eagle-i Network Grows Again

The eagle-i network grows again, welcoming The Ohio State University and now boasting over 37 academic institutions.

August 2015

IRBrely prototype 1 completed

We’re building a national IRB reliance network to reduce the administrative burden for multi-site research studies.

June 2015

iPS Cell Search at ISSCR in Stockholm, Sweden

eagle-i’s iPS cell search is the subject of “Developing a single point of truth for iPSC information: An open-sourced, semantic web approach” at the International Society for Stem Cell Research conference in Stockholm, Sweden.

June 2015

IssueMaker Launched

Webforms trigger creation of customer support tickets within an Atlassian JIRA ticketing system.

March 2015

IRB Ceded Review expanded

We now support a regional network of 36 New England institutions who rely on each other for IRB review of multi-site studies.

March 2015

iPSC search goes live on eagle-i

iPSC (induced pluripotent stem cell) search now available. Try it.

February 2015

Apply Hub for Courses

We expanded Apply Hub to include course registrations.

January 2015

Twitter and Slideshare added to Profiles

Researchers can now add Twitter or slideshare presentations to their profiles via OpenSocial gadgets

September 2014

eagle-i resources now available through Harvard Catalyst Profiles

Try it.

July 2014

First joint i2b2/SHRINE Annual Conference

The event attracts participants from across the US and around the globe. View the conference materials.

April 2014

Scheduler live at Boston Children’s Hospital

February 2014

eagle-i network expands

Ten new institutions join the eagle-i network in the last year, bringing the total to 28!

December 2013

Scheduler live at Brigham & Women’s and MGH

March 2013

Introducing Apply Hub

Apply Hub is a workflow-based system that allows funding, course or training administrators to manage the full apply-review-decide process.

March 2013

SHRINE article published in PLOS ONE

PLOS ONE is an inclusive, peer-reviewed, open-access resource from the PUBLIC LIBRARY OF SCIENCE.

December 2012

Publication on eagle-i curation process

Read the article in DATABASE: The Journal of Biological Databases and Curation

June 2012

Profiles Research Networking Software (RNS) now supports RDF standards

May 2012

The HCCRC Scheduler beta is launched at Beth Israel Deaconess Medical Center

The HCCRC Scheduler application allows study teams direct access to schedule visits in the Harvard Catalyst clinical research centers, and provides operational support for CRC staff.

September 2011

SHRINE National Pilot kicks off

A SHRINE National Pilot creates a demonstration network that will include selected academic health centers from across the United States.

August 2011

eagle-i search is open to the general public

The eagle-i consortium launches a national research resource discovery network with over 35,000 published resources.

August 2011

Dana-Farber joins the Harvard SHRINE network

SHRINE is now live at a fifth Harvard affiliated institution.
Learn more about it.

June 2011

Open.Med launches wiki is launched to support the open source software community within Harvard Catalyst and CBMI.

June 2011

First annual SHRINE conference

The first annual SHRINE conference brings together stakeholders from over 50 different organizations. Access conference materials.

June 2011

Harvard Core Facilities database is now powered by eagle-i

Harvard Catalyst Core Facilities now leverages the rich resource listings and semantic search available in the eagle-i repository.

May 2011

Online grant writing tool is launched

The Elements of Grant Writing, an online grant writing guide, goes live.

March 2011

Education Video Library goes live

A dynamic video library of courses, seminars and lectures is available on the Harvard Catalyst Portal.

October 2010

Introducing Pathfinder

Harvard Catalyst’s Pathfinder provides a new way for researchers to see how their work fits in the spectrum of activities that define clinical and translational research.


Scrubber 1.3 enhancements

Scrubber now combines autocoding and de-identification tasks to maximize utility and minimize customizations. Learn more.

October 2010

Harvard Catalyst website redesigned

Harvard Catalyst’s web presence is transformed with new tools, improved navigation, and a new look & feel. Learn more.

March 2010

Profiles Research Networking Software goes open source

Read more about it.

February 2010

A new Advanced Curriculum Compendium

This searchable catalog opens doors to educational opportunities at a growing number of Harvard Catalyst partners.

December 2009

IRB Ceded Review system launched

The IRB Cede Review Request system accelerates study initiation for multi-center trials by enabling an investigator to file paperwork to a single Institutional Review Board.

October 2009

SHRINE (Shared Health Research Information Network) is live at four hospitals

SHRINE enables clinical investigators to find potential research particiants at participating institutions.

October 2009

Protocol Review goes live

The online Protocol Review application makes it easier for investigators to access the services of the clinical research centers by centralizing the operational and scientific review processes.

September 2009

A $15 million ARRA grant funds the eagle-i consortium

Read more about it.

August 2009

Semantic Search introduced

MeSH-enabled search classifies results by people, publications, core facilities or trials, and suggests other relevant searches.

September 2008

Harvard Trials is launched

Explore clinical trials active at the 18+ institutions affiliated with Harvard Catalyst at Harvard Trials.

September 2008

Core Facilities database is launched

Locate and compare core services offered by fee-for-service labs.

September 2008

Introducing Harvard Catalyst Profiles

Harvard Catalyst Profiles enables Harvard faculty to quickly and efficiently find scientific collaborators.

September 2008

Harvard Catalyst website is launched

Read more about it.

May 2008

Harvard Medical School receives CTSA Award and Harvard Catalyst is born!

Read more about the $192 million award that established Harvard Catalyst